WKYMVm   Click here for help

GtoPdb Ligand ID: 1048

Synonyms: Trp-Lys-Tyr-Met-Val-[D]Met | WKYMVM
Immunopharmacology Ligand
Compound class: Peptide
Comment: Peptide agonist of FPR1, FPR2 and FPR3 receptors.
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Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
FPR2 Hs Agonist Full agonist 10.1 pKd - 2-5
pKd 10.1 [2-5]
FPR2 Mm Agonist Full agonist 9.0 – 10.1 pEC50 - 3-4
pEC50 9.0 – 10.1 [3-4]
FPR1 Hs Agonist Full agonist 9.0 pEC50 - 5
pEC50 9.0 [5]
FPR1 Mm Agonist Full agonist 9.0 pEC50 - 3-4
pEC50 9.0 [3-4]
FPR3 Hs Agonist Full agonist 8.5 pEC50 - 2
pEC50 8.5 (EC50 3x10-9 M) [2]