Synonyms: MM433593
Compound class:
Synthetic organic
Comment: The authors of this study claim MM-433593 is a oral, potent and selective inhibitor of fatty acid amide hydrolase-1 (FAAH1) with potential for treatment of pain, inflammation, and other disorders [1].
![]() Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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Immunopharmacology Comments |
FAAH inactivates the biologically active fatty acid amides, a family of signaling lipids that includes the endocannabinoids. Endocannabinoids are cannabinoid receptor agonists that have anti‐inflammatory and analgesic activities. Prevention of endocannabinoid degradation by FAAH enzyme inhibitors is predicted to enhance their anti‐inflammatory and analgesic effects. |