tolimidone   Click here for help

GtoPdb Ligand ID: 9433

Synonyms: CP-26154 | MLR-1023
Compound class: Synthetic organic
Comment: Tolimidone is a potent and selective allosteric activator of Lyn kinase [1]. It was developed for the treatment of type 2 diabetes.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 54.98
Molecular weight 202.07
XLogP 2.26
No. Lipinski's rules broken 0
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Canonical SMILES Cc1cccc(c1)Oc1cnc(=O)[nH]c1
Isomeric SMILES Cc1cccc(c1)Oc1cnc(=O)[nH]c1
InChI InChI=1S/C11H10N2O2/c1-8-3-2-4-9(5-8)15-10-6-12-11(14)13-7-10/h2-7H,1H3,(H,12,13,14)
Classification Click here for help
Compound class Synthetic organic
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
4543 tolimidone
Synonyms Click here for help
CP-26154 | MLR-1023
Database Links Click here for help
ChEMBL Ligand CHEMBL8030
GtoPdb PubChem SID 329968374
PubChem CID 39065
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UniChem Compound Search for chemical match using the InChIKey HJQILFPVRNHTIG-UHFFFAOYSA-N
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MLR 1023 (links to external site)
Cat. No. 4582