Compound class:
Synthetic organic
Comment: BI-9564 is an inhibitor of bromodomains in BRD7 and BRD9 [1-2]. BI-9564 is one of the compounds available from the Structural Genomics Consortium's epigenetic probes set. It was developed in collaboration with Boehringer Ingelheim.
![]() Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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References |
1. Karim RM, Schönbrunn E. (2016)
An Advanced Tool To Interrogate BRD9. J Med Chem, 59 (10): 4459-61. [PMID:27120693] |
2. Martin LJ, Koegl M, Bader G, Cockcroft XL, Fedorov O, Fiegen D, Gerstberger T, Hofmann MH, Hohmann AF, Kessler D et al.. (2016)
Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor. J Med Chem, 59 (10): 4462-75. [PMID:26914985] |
3. SCC.
BI-9564 A chemical probe for BRD9 and BRD7. Accessed on 11/12/2015. Modified on 11/12/2015. thesgc.org, http://www.thesgc.org/chemical-probes/BI-9564 |