CCL26   Click here for help

GtoPdb Ligand ID: 776

Synonyms: MIP-4α | PTEC
Immunopharmacology Ligand
Compound class: Endogenous peptide in human, mouse or rat
Comment: CCL26 is a CC family chemokine.
Species: Human
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
References
1. Blanchard C, Wang N, Stringer KF, Mishra A, Fulkerson PC, Abonia JP, Jameson SC, Kirby C, Konikoff MR, Collins MH et al.. (2006)
Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis.
J Clin Invest, 116 (2): 536-47. [PMID:16453027]
2. Kitaura M, Suzuki N, Imai T, Takagi S, Suzuki R, Nakajima T, Hirai K, Nomiyama H, Yoshie O. (1999)
Molecular cloning of a novel human CC chemokine (Eotaxin-3) that is a functional ligand of CC chemokine receptor 3.
J Biol Chem, 274 (39): 27975-80. [PMID:10488147]
3. Morokata T, Suzuki K, Masunaga Y, Taguchi K, Morihira K, Sato I, Fujii M, Takizawa S, Torii Y, Yamamoto N et al.. (2006)
A novel, selective, and orally available antagonist for CC chemokine receptor 3.
J Pharmacol Exp Ther, 317 (1): 244-50. [PMID:16339911]
4. Parody TR, Stone MJ. (2004)
High level expression, activation, and antagonism of CC chemokine receptors CCR2 and CCR3 in Chinese hamster ovary cells.
Cytokine, 27 (1): 38-46. [PMID:15207250]