onternabez   Click here for help

GtoPdb Ligand ID: 746

Synonyms: HU-308 | HU308 | LS-193061
Compound class: Synthetic organic
Comment: HU308 is a synthetic cannabinoid. Its acts as a CB2 receptor agonist and has anti-inflammatory activity. The chemical structure of HU308 matches that for the INN compound onternabez that was surfaced in WHO Proposed list 125 in July 2021.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 10
Topological polar surface area 38.69
Molecular weight 414.31
XLogP 8.07
No. Lipinski's rules broken 1
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Canonical SMILES CCCCCCC(c1cc(OC)c(c(c1)OC)C1C=C(CO)C2CC1C2(C)C)(C)C
Isomeric SMILES CCCCCCC(c1cc(OC)c(c(c1)OC)[C@H]1C=C(CO)[C@@H]2C[C@H]1C2(C)C)(C)C
InChI InChI=1S/C27H42O3/c1-8-9-10-11-12-26(2,3)19-14-23(29-6)25(24(15-19)30-7)20-13-18(17-28)21-16-22(20)27(21,4)5/h13-15,20-22,28H,8-12,16-17H2,1-7H3/t20-,21-,22+/m0/s1
Classification Click here for help
Compound class Synthetic organic
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
11976 onternabez
Synonyms Click here for help
HU-308 | HU308 | LS-193061
Database Links Click here for help
Specialist databases
GPCRdb Ligand onternabez
Other databases
BindingDB Ligand 50265621
CAS Registry No. 256934-39-1 (source: WHO INN record)
ChEMBL Ligand CHEMBL497392
GtoPdb PubChem SID 135650356
PubChem CID 9844711
Search Google for chemical match using the InChIKey CFMRIVODIXTERW-FDFHNCONSA-N
Search Google for chemicals with the same backbone CFMRIVODIXTERW
Search PubMed clinical trials onternabez
Search PubMed titles onternabez
Search PubMed titles/abstracts onternabez
UniChem Compound Search for chemical match using the InChIKey CFMRIVODIXTERW-FDFHNCONSA-N
UniChem Connectivity Search for chemical match using the InChIKey CFMRIVODIXTERW-FDFHNCONSA-N
Wikipedia HU-308