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siltuximab   Click here for help

GtoPdb Ligand ID: 7396

Synonyms: cLLB8 | CNTO 328 | Sylvant®
Approved drug Immunopharmacology Ligand
siltuximab is an approved drug (EMA & FDA (2014))
Compound class: Antibody
Comment: Siltuximab is a monoclonal antibody targeting interleukin 6 (IL-6) [6].
Peptide sequences for the heavy and light chains of this antibody are annotated in its IMGT/mAb-DB record. The invention of siltuximab is claimed in patent US7291721 [2].
Immunopharmacology Comments
Siltuximab is a drug for an orphan (rare) disease.
Immunopharmacology Disease
Disease X-Refs Comment References
Multicentric Castleman disease OMIM: 148000
Orphanet: ORPHA93686
 Approved therapeutic for MCD.