methazolamide   Click here for help

GtoPdb Ligand ID: 6828

Synonyms: methenamide | Neptazane®
Approved drug
methazolamide is an approved drug (FDA (1959))
Compound class: Synthetic organic
Comment: Inhibits carbonic anhydrases. This compound is also represented on ChEMBL by the entry with ID CHEMBL19.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 144.03
Molecular weight 236
XLogP -0.98
No. Lipinski's rules broken 0
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Canonical SMILES CC(=O)N=c1sc(nn1C)S(=O)(=O)N
Isomeric SMILES CC(=O)N=c1sc(nn1C)S(=O)(=O)N
InChI InChI=1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12)
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1959))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
882 methazolamide
Synonyms Click here for help
methenamide | Neptazane®
Database Links Click here for help
CAS Registry No. 554-57-4
ChEMBL Ligand CHEMBL1335656
DrugBank Ligand DB00703
DrugCentral Ligand 1741
GtoPdb PubChem SID 178103434
PubChem CID 4100
Search Google for chemical match using the InChIKey FLOSMHQXBMRNHR-UHFFFAOYSA-N
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SynPHARM 78861 (in complex with carbonic anhydrase 1)
UniChem Compound Search for chemical match using the InChIKey FLOSMHQXBMRNHR-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey FLOSMHQXBMRNHR-UHFFFAOYSA-N
Wikipedia Methazolamide