IL-17A/IL-17F   Click here for help

GtoPdb Ligand ID: 5874

Immunopharmacology Ligand
Comment: Heterodimeric ligand.
Species: Human
Natural/Endogenous Targets
Target
Interleukin-17 receptor
Selectivity at catalytic receptors
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
Interleukin-17 receptor Ligand is endogenous in the given species Hs Agonist Agonist - - -
Other ligands which bind to or alter the activity of this ligand
Key to terms and symbols Click column headers to sort
Ligand Sp. Type Action Value Parameter Concentration range (M) Reference
xeligekimab Peptide Approved drug Primary target of this compound Hs Antibody Binding 8.6 pKd - 1
pKd 8.6 (Kd 2.47x10-9 M) [1]
Description: Binding affinity determined by SPR