GtoPdb is requesting financial support from commercial users. Please see our sustainability page for more information.
| 
                               
                            
                                
                                                                Synonyms: 40S ribosomal protein S6 | phosphoprotein NP33 | rpS6
                                 
                                                         
                            Compound class: 
                                                            Endogenous peptide in human, mouse or rat
                                 
                                
                                    Species: Human
                                 
                            
                            
                          
                                
                                    
                                
                          
                                   
                                   
                                  
                                    
                                    
                                     | 
                                    
| Targets where the ligand is described in the comment field | |
| Target | Comment | 
| SGK494 | Ribosomal S6 kinase 90 kDa serine/threonine kinases, also known as p90rsk or MAPK-activated protein kinase-1 (MAPKAP-K1), are activated by MAP kinase -mediated phosphorylation. RSK protein kinases are also activated by phosphorylation by TORC1 [1,3] and PDK1 [2]. Substrates include ribosomal protein S6 (RPS6, P62753), GSK3β (P49841) [5] and the 5HT2A receptor [4]. |