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growth/differentiation factor-11   Click here for help

GtoPdb Ligand ID: 4876

Synonyms: BMP11 | bone morphogenetic protein 11 | GDF-11
Compound class: Endogenous peptide in human, mouse or rat
Comment: The active peptide is a disulphide bond-linked homodimer
Species: Human
Peptide Sequence Click here for help
NLGLDCDEHSSESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGQCEYMFMQKYPHTHLVQQANPRGSAGPCCTPTKMS
PINMLYFNDKQQIIYGKIPGMVVDRCGCS
Post-translational Modification
The active peptide is a homodimer linked by a disulphide bond between cysteine residues at position 73 of each chain. Predicted disulphide bond formation between cysteine residues at positions 15 and 74, 43 and 106, and 47 and 108