Synonyms: buserelin acetate | HOE 766 | HOE 766A | ICI 123215 | Metrelef® | Suprefact®
buserelin is an approved drug
Compound class:
Peptide
Comment: Buserelin is a GnRH (luteinizing hormone-releasing hormone, LHRH) agonist. Buserelin does not appear to have marketing approval for human use in the US or EU, although individual countries may have approved use of this drug.
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
Classification | |
Compound class | Peptide |
Approved drug? | Yes |
IUPAC Name |
(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-(ethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(3H-imidazol-4-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide |
International Nonproprietary Names | |
INN number | INN |
4045 | buserelin |
Synonyms |
buserelin acetate | HOE 766 | HOE 766A | ICI 123215 | Metrelef® | Suprefact® |
Database Links | |
Specialist databases | |
GPCRdb Ligand | buserelin |
Other databases | |
CAS Registry No. | 57982-77-1 (source: Scifinder) |
ChEMBL Ligand | CHEMBL2110824 |
DrugBank Ligand | DB06719 |
DrugCentral Ligand | 436 |
GtoPdb PubChem SID | 178100699 |
PubChem CID | 50225 |
Search Google for chemical match using the InChIKey | CUWODFFVMXJOKD-UVLQAERKSA-N |
Search Google for chemicals with the same backbone | CUWODFFVMXJOKD |
Search PubMed clinical trials | buserelin |
Search PubMed titles | buserelin |
Search PubMed titles/abstracts | buserelin |
UniChem Compound Search for chemical match using the InChIKey | CUWODFFVMXJOKD-UVLQAERKSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | CUWODFFVMXJOKD-UVLQAERKSA-N |
Wikipedia | Buserelin |