neuromedin N   Click here for help

GtoPdb Ligand ID: 1578

Synonyms: NN
Compound class: Endogenous peptide in human, mouse or rat
Comment: As with many peptides there is some ambiguity surrounding the exact chemical structure and chirality of neuromedin N. We have chosen not to display a chemical structure here, but for representations of the structure, please see the entry on PubChem linked to above and that corresponding to the CAS registry number.
Species: Mouse, Rat
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species

neuromedin N is commercially available from our sponsors

References
1. Botto JM, Chabry J, Sarret P, Vincent JP, Mazella J. (1998)
Stable expression of the mouse levocabastine-sensitive neurotensin receptor in HEK 293 cell line: binding properties, photoaffinity labeling, and internalization mechanism.
Biochem Biophys Res Commun, 243 (2): 585-90. [PMID:9480852]
2. Chalon P, Vita N, Kaghad M, Guillemot M, Bonnin J, Delpech B, Le Fur G, Ferrara P, Caput D. (1996)
Molecular cloning of a levocabastine-sensitive neurotensin binding site.
FEBS Lett, 386 (2-3): 91-4. [PMID:8647296]
3. Skrzydelski D, Lhiaubet AM, Lebeau A, Forgez P, Yamada M, Hermans E, Rostene W, Pelaprat D. (2003)
Differential involvement of intracellular domains of the rat NTS1 neurotensin receptor in coupling to G proteins: a molecular basis for agonist-directed trafficking of receptor stimulus.
Mol Pharmacol, 64 (2): 421-9. [PMID:12869647]