FAM150A

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Ligands
FAM150A (Human)

GtoPdb Ligand ID: 14203

Synonyms: AUG-β | augmentor-β | augmentor-beta

Compound class: Endogenous peptide in human, mouse or rat

Comment: FAM150A (AUG-β) is an endogenous leukocyte receptor tyrosine kinase (LTK) activating ligand [1-2].

Species: Human

Summary
Biological activity
References
Structure

References
1. Guan J, Umapathy G, Yamazaki Y, Wolfstetter G, Mendoza P, Pfeifer K, Mohammed A, Hugosson F, Zhang H, Hsu AW et al.. (2015) FAM150A and FAM150B are activating ligands for anaplastic lymphoma kinase. Elife, 4: e09811. [PMID:26418745]
2. Reshetnyak AV, Murray PB, Shi X, Mo ES, Mohanty J, Tome F, Bai H, Gunel M, Lax I, Schlessinger J. (2015) Augmentor α and β (FAM150) are ligands of the receptor tyrosine kinases ALK and LTK: Hierarchy and specificity of ligand-receptor interactions. Proc Natl Acad Sci U S A, 112 (52): 15862-7. [PMID:26630010]

References

1. Guan J, Umapathy G, Yamazaki Y, Wolfstetter G, Mendoza P, Pfeifer K, Mohammed A, Hugosson F, Zhang H, Hsu AW et al.. (2015)
FAM150A and FAM150B are activating ligands for anaplastic lymphoma kinase.
Elife, 4: e09811. [PMID:26418745]

2. Reshetnyak AV, Murray PB, Shi X, Mo ES, Mohanty J, Tome F, Bai H, Gunel M, Lax I, Schlessinger J. (2015)
Augmentor α and β (FAM150) are ligands of the receptor tyrosine kinases ALK and LTK: Hierarchy and specificity of ligand-receptor interactions.
Proc Natl Acad Sci U S A, 112 (52): 15862-7. [PMID:26630010]