D1SP   Click here for help

GtoPdb Ligand ID: 13660

Compound class: Peptide
Comment: D1SP is a synthetic protein containing a membrane-targeting signal sequence, the PlexinD1 ligand (semaphorin) binding and PSI domains (aa 49-601) fused (via a linker and hinge region) to a human IgG1 Fc domain. It was desgned to block Sema3 ligand binding to the PlexinD1 receptor [1].
Selectivity at other protein targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
plexin D1 Hs Inhibitor Inhibition - - - 1
[1]