Synonyms: example 31 [CN106366093A] | MAX-40279 | MAX-40279-01 | MAX40279
Compound class:
Synthetic organic
Comment: The chemical structure for INN nefextinib (proposed INN list 130, Feb. 2024) matches PubChem CID 126495573, and onto the company research code MAX-40279 which is an orally bioavailable, dual FLT3/FGFR receptor tyrosine kinase inhibitor.
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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References |
1. Xu Z, Zhang N, Wang T, Sun Q, Wang Y. (2017)
Fused pyrimidine compound, and intermediate, preparation method, composition and application of. Patent number: CN106366093A. Assignee: Guangzhou Re Pharmaceutical Technology Co Ltd. Priority date: 21/07/2016. Publication date: 01/02/2017. |