sugemalimab   Click here for help

GtoPdb Ligand ID: 12342

Synonyms: Cejemly® (China) | CS-1001 | CS1001 | WBP-3155 | WBP3155
Approved drug
sugemalimab is an approved drug (China (2021), EMA (2024))
Compound class: Antibody
Comment: Sugemalimab is a fully human, high-affinity anti-programmed death ligand 1 (PD-L1) IgG4 monoclonal antibody. It is a checkpoint inhibitor class immuno therapeutic. In vitro, it competitively blocks the binding of human PD-L1 to PD-1 and CD80, and it induces T lymphocyte proliferation and enhances antitumour immunity [2].
Selectivity at ligand targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
programmed cell death 1 ligand 1 Hs Antibody Binding - - - 2
⤷ [2]