EK-1-C4   Click here for help

GtoPdb Ligand ID: 11501

Synonyms: EK1C4
Comment: This is the lipopeptide version of EK-1 [1]. It has cholesterol fused at the C terminal via a short peptide linker and a flexible polyethylene glycol (PEG) spacer. Like EK-1 it acts as a viral fusion inhibitor that blocks infection by a range of human coronavirus pseudoviruses and live viruses, including SARS-Co-V and SARS-CoV-2. It is significantly more potent than EK-1, and is active in vitro and in vivo.
Classification Click here for help
Compound class Peptide or derivative
Synonyms Click here for help
EK1C4
Database Links Click here for help
GtoPdb PubChem SID 441604873