Synonyms: EK1C4
Compound class:
Peptide or derivative
Comment: This is the lipopeptide version of EK-1 [1]. It has cholesterol fused at the C terminal via a short peptide linker and a flexible polyethylene glycol (PEG) spacer. Like EK-1 it acts as a viral fusion inhibitor that blocks infection by a range of human coronavirus pseudoviruses and live viruses, including SARS-Co-V and SARS-CoV-2. It is significantly more potent than EK-1, and is active in vitro and in vivo.
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Classification ![]() |
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Compound class | Peptide or derivative |
Synonyms ![]() |
EK1C4 |
Database Links ![]() |
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GtoPdb PubChem SID | 441604873 |