EK-1-C4   Click here for help

GtoPdb Ligand ID: 11501

Synonyms: EK1C4
Comment: This is the lipopeptide version of EK-1 [1]. It has cholesterol fused at the C terminal via a short peptide linker and a flexible polyethylene glycol (PEG) spacer. Like EK-1 it acts as a viral fusion inhibitor that blocks infection by a range of human coronavirus pseudoviruses and live viruses, including SARS-Co-V and SARS-CoV-2. It is significantly more potent than EK-1, and is active in vitro and in vivo.
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Compound class Peptide or derivative
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Database Links Click here for help
GtoPdb PubChem SID 441604873