pirbenicillin

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Ligands
pirbenicillin

GtoPdb Ligand ID: 10845

Synonyms: CP-33,994 | CP-33,994-2

Compound class: Synthetic organic

Comment: Pirbenicillin is a semisynthetic penicillin with antibacterial activity against Gram-positive and Gram-negative bacteria [1].

2D Structure

Physico-chemical Properties

Hydrogen bond acceptors	11
Hydrogen bond donors	4
Rotatable bonds	10
Topological polar surface area	192.38
Molecular weight	510.17
XLogP	-2.16
No. Lipinski's rules broken	1

Generated using the Chemistry Development Kit (CDK) (Willighagen EL et al. Journal of Cheminformatics vol. 9:33. 2017, doi:10.1186/s13321-017-0220-4; https://cdk.github.io/)

SMILES / InChI / InChIKey

Canonical SMILES	O=C(N[C@@H](C(=O)N[C@@H]1C(=O)N2[C@@H]1SC([C@@H]2C(=O)O)(C)C)c1ccccc1)CN=C(c1ccncc1)N
Isomeric SMILES	O=C(N[C@@H](C(=O)N[C@@H]1C(=O)N2[C@@H]1SC([C@@H]2C(=O)O)(C)C)c1ccccc1)CN=C(c1ccncc1)N
InChI	InChI=1S/C24H26N6O5S/c1-24(2)18(23(34)35)30-21(33)17(22(30)36-24)29-20(32)16(13-6-4-3-5-7-13)28-15(31)12-27-19(25)14-8-10-26-11-9-14/h3-11,16-18,22H,12H2,1-2H3,(H2,25,27)(H,28,31)(H,29,32)(H,34,35)/t16-,17-,18+,22-/m1/s1
InChI Key	WRFCGBVLTRJBKN-QSNWEANLSA-N

Generated using the Chemistry Development Kit (CDK) (Willighagen EL et al. Journal of Cheminformatics vol. 9:33. 2017, doi:10.1186/s13321-017-0220-4; https://cdk.github.io/)