GPR15L (71-81)   Click here for help

GtoPdb Ligand ID: 10568

Compound class: Endogenous peptide in human, mouse or rat
Comment: This peptide is a variant of GPR15L. It exhibits agonist activity at GPR15 [1].
Species: Human
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
2D Structure
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2D Structure

An image of the ligand's 2D structure. For small molecules with SMILES these are drawn using the NCI/CADD Chemical Identifier Resolver. Click on the image to access the chemical structure search tool with the ligand pre-loaded in the structure editor. For other types of ligands, e.g. longer nucleotides and peptides, a manually drawn representation of the molecule may be provided.

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SMILES / InChI / InChIKey
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SMILES / InChI / InChIKey

SMILES (Simplified Molecular Input Line Entry Specification) A specification for unambiguously describing the structure of chemical molecules using short ASCII strings. Canonical SMILES specify a unique representation of the 2D structure without chiral or isotopic specifications. Isomeric SMILES include chiral specification and isotopes.

Standard InChI (IUPAC International Chemical Identifier) and InChIKey InChI is a non-proprietary, standard, textual identifier for chemical substances designed to facilitate linking of information and database searching. An InChIKey is a simplified version of a full InChI, designed for easier web searching.

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Canonical SMILES CC(CC(C(=O)N1CCCC1C(=O)NC(C(=O)NC(C(=O)O)C(C)C)CCC(=O)N)NC(=O)C(NC(=O)CNC(=O)C1CCCN1C(=O)C(C(C)C)NC(=O)C(C(C)C)NC(=O)C(Cc1c[nH]c2c1cccc2)NC(=O)C(CC(C)C)N)C)C
Isomeric SMILES CC(C[C@@H](C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)O)C(C)C)CCC(=O)N)NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc1c[nH]c2c1cccc2)NC(=O)[C@H](CC(C)C)N)C)C
InChI InChI=1S/C58H91N13O13/c1-29(2)24-37(59)50(75)65-40(26-35-27-61-38-17-13-12-16-36(35)38)52(77)67-46(31(5)6)55(80)68-47(32(7)8)57(82)71-23-14-18-42(71)53(78)62-28-45(73)63-34(11)49(74)66-41(25-30(3)4)56(81)70-22-15-19-43(70)54(79)64-39(20-21-44(60)72)51(76)69-48(33(9)10)58(83)84/h12-13,16-17,27,29-34,37,39-43,46-48,61H,14-15,18-26,28,59H2,1-11H3,(H2,60,72)(H,62,78)(H,63,73)(H,64,79)(H,65,75)(H,66,74)(H,67,77)(H,68,80)(H,69,76)(H,83,84)/t34-,37-,39-,40-,41-,42-,43-,46-,47-,48-/m0/s1
InChI Key NLEQDIXNHJSWHA-UPULOONWSA-N
Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
GPR15LG G protein-coupled receptor 15 ligand Human protein GPR15L precursor C10orf99, chromosome 10 open reading frame 99
Database Links Click here for help
Specialist databases
GPCRdb Ligand GPR15L (71-81)
Other databases
Ensembl Gene ENSG00000188373 (Hs)
GtoPdb PubChem SID 404859015
Human Protein Atlas ENSG00000188373 (Hs)
PubChem CID 145996511
Search Google for chemical match using the InChIKey NLEQDIXNHJSWHA-UPULOONWSA-N
Search Google for chemicals with the same backbone NLEQDIXNHJSWHA
UniChem Compound Search for chemical match using the InChIKey NLEQDIXNHJSWHA-UPULOONWSA-N
UniChem Connectivity Search for chemical match using the InChIKey NLEQDIXNHJSWHA-UPULOONWSA-N
UniProtKB Q6UWK7 (Hs)