bulaquine

Ligand id: 10414

Name: bulaquine

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 72.48
Molecular weight 369.21
XLogP 3.37
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Ligand families/groups Antimalarial ligands
IUPAC Name
(3E)-3-[1-[4-[(6-methoxyquinolin-8-yl)amino]pentylamino]ethylidene]oxolan-2-one
International Nonproprietary Names
INN number INN
7927 bulaquine
Synonyms
CDRI-80/53 | elubaquine
Comments
Bulaquine is an 8-aminoquinoline derivative that has antimalarial activity and is a synthetic analogue of primaquine.
The INN record for bulaquine indicates that it is a racemic mixture.

The Malaria tab on this ligand page provides additional curator comments of relevance to the Guide to MALARIA PHARMACOLOGY.
Database Links
CAS Registry No. 79781-00-3 (source: Scifinder)
ChEMBL Ligand CHEMBL2106578
GtoPdb PubChem SID 385612174
PubChem CID 3036820
Search Google for chemical match using the InChIKey ADCOUXIGWFEYJP-OBGWFSINSA-N
Search Google for chemicals with the same backbone ADCOUXIGWFEYJP
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Search UniChem for chemical match using the InChIKey ADCOUXIGWFEYJP-OBGWFSINSA-N
Search UniChem for chemicals with the same backbone ADCOUXIGWFEYJP