ML10

Ligand id: 10225

Name: ML10

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 100.87
Molecular weight 508.21
XLogP 4.38
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Ligand families/groups Antimalarial ligands
IUPAC Name
N-[5-[3-[2-(cyclopropylmethyl)pyrimidin-4-yl]-7-[(dimethylamino)methyl]-6-methylimidazo[1,2-a]pyridin-2-yl]-2-fluorophenyl]methanesulfonamide
Comments
ML10 is the lead compound from an imidazopyridine series with antimalarial activity [1].

The Malaria tab on this ligand page provides additional curator comments of relevance to the Guide to MALARIA PHARMACOLOGY.
Database Links
GtoPdb PubChem SID 381744907
PubChem CID 137553160
Search Google for chemical match using the InChIKey VRZZXBIIWWZFEI-UHFFFAOYSA-N
Search Google for chemicals with the same backbone VRZZXBIIWWZFEI
Search UniChem for chemical match using the InChIKey VRZZXBIIWWZFEI-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone VRZZXBIIWWZFEI