endothelin-3   Click here for help

GtoPdb Ligand ID: 1004

Abbreviated name: ET-3
Compound class: Endogenous peptide in human, mouse or rat
Comment: The human ET-3 sequence is identical to the mouse and rat ET-3 sequences.
Species: Human, Mouse, Rat
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Neuropeptides
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
EDN3 endothelin 3 Human prepro-endothelin 3 ET3
Edn3 endothelin 3 Mouse prepro-endothelin 3 114CH19, 114-CH19, tmgc48
Edn3 endothelin 3 Rat prepro-endothelin 3 edn3_mapped, endothelin 3, endothelin-3, endothelin 3 (mapped), Et3, ET-3, LOC502697, PPET3, preproendothelin-3, preproET-3, RGD1564825, similar to prepro-endothelin-3
Database Links Click here for help
Specialist databases
GPCRdb Ligand endothelin-3
Other databases
CAS Registry No. 125692-40-2
Ensembl Gene ENSG00000124205 (Hs), ENSMUSG00000027524 (Mm)
GtoPdb PubChem SID 135651744
Human Protein Atlas ENSG00000124205 (Hs)
PubChem CID 16219334
UniProtKB P13207 (Rn), P48299 (Mm), P14138 (Hs)