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Rho kinase C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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Rho kinase (also known as P160ROCK, Rho-activated kinase) is activated by members of the Rho small G protein family, which are activated by GTP exchange factors, such as ARHGEF1 (Q92888, p115-RhoGEF), which in turn may be activated by Gα12/13 subunits [4].

Enzymes

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Rho kinase 1 (Rho associated coiled-coil containing protein kinase 1 / ROCK1) C Show summary » More detailed page go icon to follow link

Rho kinase 2 (Rho associated coiled-coil containing protein kinase 2 / ROCK2) C Show summary » More detailed page go icon to follow link

Further reading

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References

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How to cite this family page

Database page citation:

Rho kinase. Accessed on 11/12/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=289.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.