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Sodium-dependent HCO3- transporters C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Transporters

911
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NBCe1 (Electrogenic sodium bicarbonate cotransporter 1 / SLC4A4) C Show summary »

NBCe2 (Electrogenic sodium bicarbonate cotransporter 4 / SLC4A5) C Show summary »

NBCn1 (Electroneutral sodium bicarbonate cotransporter 1 / SLC4A7) C Show summary »

NBCn2 (Electroneutral sodium bicarbonate cotransporter 2 / SLC4A10) C Show summary »

Target Id 911
Nomenclature Electroneutral sodium bicarbonate cotransporter 2
Systematic nomenclature SLC4A10
Common abbreviation NBCn2
Previous and unofficial names NCBE | solute carrier family 4, sodium bicarbonate transporter-like, member 10 | solute carrier family 4 member 10 | solute carrier family 4, sodium bicarbonate cotransporter-like, member 10 | solute carrier family 4
Genes SLC4A10 (Hs), Slc4a10 (Mm), Slc4a10 (Rn)
Ensembl ID ENSG00000144290 (Hs), ENSMUSG00000026904 (Mm), ENSRNOG00000005307 (Rn)
UniProtKB AC Q6U841 (Hs), Q5DTL9 (Mm), Q80ZA5 (Rn)
Bioparadigms SLC Tables SLC4A10 (Hs)
RESOLUTE SLC4A10 (Hs)
Endogenous substrates
NaHCO3
Stoichiometry 1 Na+ : 1 HCO3- (out) or 1 Na : CO32*

NDCBE (NBCBE / SLC4A8) C Show summary »

BTR1 (NaBC1 / SLC4A11) C Show summary »

How to cite this family page

Database page citation:

Sodium-dependent HCO3- transporters. Accessed on 14/08/2026. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=171.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Gibb AJ, Kelly E, Mathie AA, Peach CJ, Veale EL, Armstrong JF, Faccenda E, Harding SD, Southan C, Davies JA et al. (2025) The Concise Guide to PHARMACOLOGY 2025/26: Transporters. Br J Pharmacol. 182: S404-S496.