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Target id: 2899
Nomenclature: Guanylyl cyclase-F
Abbreviated Name: GC-F
Family: Transmembrane guanylyl cyclases
Gene and Protein Information ![]() |
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Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
Human | 1 | 1108 | Xq22.3-q23 | GUCY2F | guanylate cyclase 2F, retinal | |
Mouse | 1 | 1108 | X 62.85 cM | Gucy2f | guanylate cyclase 2f | |
Rat | 1 | 1108 | Xq33 | Gucy2f | guanylate cyclase 2F |
Previous and Unofficial Names ![]() |
RetGC-2 | ROS-GC2 | guanylate cyclase 2F, retinal | Ret2-GC |
Database Links ![]() |
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Alphafold | P51841 (Hs), Q5SDA5 (Mm), P51842 (Rn) |
CATH/Gene3D | 3.30.70.1230 |
Ensembl Gene | ENSG00000101890 (Hs), ENSMUSG00000042282 (Mm), ENSRNOG00000019086 (Rn) |
Human Protein Atlas | ENSG00000101890 (Hs) |
Pharos | P51841 (Hs) |
UniProtKB | P51841 (Hs), Q5SDA5 (Mm), P51842 (Rn) |
Wikipedia | GUCY2F (Hs) |
Natural/Endogenous Ligands ![]() |
guanylyl cyclase-activating protein 1 {Sp: Human, Mouse, Rat} |
guanylyl cyclase-activating protein 2 {Sp: Human, Mouse, Rat} |
Localisation |
Retinal photoreceptors |
Principal function(s) |
Vision/phototransduction |
Download all structure-activity data for this target as a CSV file
Activators | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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