Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	-	567	16q12.2	CES1	carboxylesterase 1
Mouse	-	565	8 45.29 cM	Ces1g	carboxylesterase 1G
Rat	-	565	19p11	Ces1d	carboxylesterase 1D

Previous and Unofficial Names

CEH | HMSE1 | monocyte/macrophage serine esterase 1 | SES1

Database Links
Specialist databases
MEROPS	S09.982 (Hs)
Other databases
Alphafold	P23141 (Hs), Q8VCC2 (Mm), P16303 (Rn)
BRENDA	3.1.1.1
CATH/Gene3D	3.40.50.1820
ChEMBL Target	CHEMBL2265 (Hs), CHEMBL4105953 (Mm)
DrugBank Target	P23141 (Hs)
Ensembl Gene	ENSG00000198848 (Hs), ENSMUSG00000057074 (Mm), ENSRNOG00000015438 (Rn), ENSRNOG00000015519 (Rn)
Entrez Gene	1066 (Hs), 12623 (Mm), 113902 (Rn)
Human Protein Atlas	ENSG00000198848 (Hs)
KEGG Enzyme	3.1.1.1
KEGG Gene	hsa:1066 (Hs), mmu:12623 (Mm), rno:113902 (Rn)
OMIM	605278 (Hs)
Pharos	P23141 (Hs)
RefSeq Nucleotide	NM_001025194 (Hs), NM_021456 (Mm), NM_133295 (Rn)
RefSeq Protein	NP_001020365 (Hs), NP_067431 (Mm), NP_579829 (Rn)
UniProtKB	P23141 (Hs), Q8VCC2 (Mm), P16303 (Rn)
Wikipedia	CES1 (Hs)

Enzyme Reaction
EC Number: 3.1.1.1

Download all structure-activity data for this target as a CSV file

Inhibitors
Key to terms and symbols	View all chemical structures	Click column headers to sort
Ligand Sp. Action Value Parameter Reference GR148672X Hs Inhibition 8.4 pIC50 1 ⤷ pIC50 8.4 (IC50 4x10-9 M) [1]