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Interleukin-4 receptor type II

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Target id: 2299

Nomenclature: Interleukin-4 receptor type II

Family: IL-2 receptor family

Quaternary Structure: Subunits
Interleukin-4 receptor subunit α (Ligand-binding subunit)
Interleukin-13 receptor subunit α1 (Other subunit)
Previous and Unofficial Names Click here for help
interleukin-13 receptor
Natural/Endogenous Ligands Click here for help
IL-13 {Sp: Human}
IL-4 {Sp: Human}

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Agonists
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Ligand Sp. Action Value Parameter Reference
IL-13 {Sp: Human} Peptide Ligand is endogenous in the given species Immunopharmacology Ligand Hs Agonist - -
IL-4 {Sp: Human} Peptide Click here for species-specific activity table Ligand is endogenous in the given species Immunopharmacology Ligand Hs Agonist - -
Immunopharmacology Comments
IL-4R type II is a heterodimer of the IL4RA (ligand binding subunit) and IL13RA1 (signal transducing subunit). It binds IL-4 and IL-13.

How to cite this page

IL-2 receptor family: Interleukin-4 receptor type II. Last modified on 11/04/2017. Accessed on 15/10/2024. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetomalariapharmacology.org/GRAC/ObjectDisplayForward?objectId=2299.