Quaternary Structure: Complexes

Interleukin-15 receptor

Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	1	267	10p15.1	IL15RA	interleukin 15 receptor subunit alpha
Mouse	1	263	2 8.97 cM	Il15ra	interleukin 15 receptor, alpha chain
Rat	-	-		Il15ra	interleukin 15 receptor subunit alpha

Previous and Unofficial Names

CD215 | interleukin 15 receptor, alpha | interleukin 15 receptor

Database Links
Alphafold	Q13261 (Hs), Q60819 (Mm)
ChEMBL Target	CHEMBL4665592 (Hs)
Ensembl Gene	ENSG00000134470 (Hs), ENSMUSG00000023206 (Mm), ENSRNOG00000018706 (Rn)
Entrez Gene	3601 (Hs), 16169 (Mm), 690369 (Rn)
Human Protein Atlas	ENSG00000134470 (Hs)
KEGG Gene	hsa:3601 (Hs), mmu:16169 (Mm), rno:690369 (Rn)
OMIM	601070 (Hs)
Pharos	Q13261 (Hs)
UniProtKB	Q13261 (Hs), Q60819 (Mm)
Wikipedia	IL15RA (Hs)

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Agonists
Key to terms and symbols		Click column headers to sort
Ligand Sp. Action Value Parameter Reference IL-15 {Sp: Human} Hs Agonist 11.4 pKd 1 ⤷ pKd 11.4 (Kd 3.8x10-12 M) [1] Description: Binding of recombinant hIL-15 to IL-15Rα subunit using Surface Plasmon Resonance (SPR)

Immunopharmacology Comments

This is the ligand binding subunit of the functional IL-15 receptor complex.

Immuno Process Associations

Immuno Process:  Cytokine production & signalling

Immuno Process:  Inflammation

Immuno Process:  Cellular signalling

Immuno Process:  Immune regulation

Immuno Process:  Immune system development