Quaternary Structure: Complexes

Interleukin-4 receptor type II

Gene and Protein Information
Species	TM	AA	Chromosomal Location	Gene Symbol	Gene Name	Reference
Human	1	427	Xq24	IL13RA1	interleukin 13 receptor subunit alpha 1
Mouse	1	424	X 20.49 cM	Il13ra1	interleukin 13 receptor, alpha 1
Rat	-	-		Il13ra1	interleukin 13 receptor subunit alpha 1

Previous and Unofficial Names

CD213a1 | NR4 | IL13 receptor alpha-1 chain | interleukin 13 receptor, alpha 1 | interleukin 13 receptor

Database Links
Alphafold	P78552 (Hs), O09030 (Mm)
CATH/Gene3D	2.60.40.10
ChEMBL Target	CHEMBL3831285 (Hs)
Ensembl Gene	ENSG00000131724 (Hs), ENSMUSG00000017057 (Mm), ENSRNOG00000001713 (Rn), ENSRNOG00000013170 (Rn)
Entrez Gene	3597 (Hs), 16164 (Mm), 252963 (Rn)
Human Protein Atlas	ENSG00000131724 (Hs)
KEGG Gene	hsa:3597 (Hs), mmu:16164 (Mm), rno:252963 (Rn)
OMIM	300119 (Hs)
Pharos	P78552 (Hs)
UniProtKB	P78552 (Hs), O09030 (Mm)
Wikipedia	IL13RA1 (Hs)

Download all structure-activity data for this target as a CSV file

Antibodies
Key to terms and symbols		Click column headers to sort
Antibody Sp. Action Value Parameter Reference eblasakimab Hs Binding 10.6 pKd 1 ⤷ pKd 10.6 (Kd 2.7x10-11 M) [1] Description: Binding affinity of full-length antibody 10G5-6 for hIL13Rα1, determined by proprietary KINEXA assay.

Immunopharmacology Comments

Interleukin-13 receptor subunit α1 is a component of the functional receptors that mediate the pro-inflammatory actions of the cytokines IL-4 and IL-13.

Immuno Process Associations

Immuno Process:  Cytokine production & signalling