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Gene and Protein Information ![]() |
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Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
Human | - | 475 | 2q35 | DNPEP | aspartyl aminopeptidase | |
Mouse | - | 473 | 1 C4 | Dnpep | aspartyl aminopeptidase | |
Rat | - | 475 | 9q33 | Dnpep | aspartyl aminopeptidase |
Previous and Unofficial Names ![]() |
ASPEP | DAP | cytosolic aminopeptidase |
Database Links ![]() |
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Specialist databases | |
MEROPS | M18.002 (Hs) |
Other databases | |
Alphafold | Q9ULA0 (Hs), Q9Z2W0 (Mm), Q4V8H5 (Rn) |
BRENDA | 3.4.11.21 |
ChEMBL Target | CHEMBL2761 (Hs) |
Ensembl Gene | ENSG00000123992 (Hs), ENSMUSG00000026209 (Mm), ENSRNOG00000019772 (Rn) |
Entrez Gene | 23549 (Hs), 13437 (Mm), 301529 (Rn) |
Human Protein Atlas | ENSG00000123992 (Hs) |
KEGG Enzyme | 3.4.11.21 |
KEGG Gene | hsa:23549 (Hs), mmu:13437 (Mm), rno:301529 (Rn) |
OMIM | 611367 (Hs) |
Pharos | Q9ULA0 (Hs) |
RefSeq Nucleotide | NM_012100 (Hs), NM_016878 (Mm), NM_001110831 (Mm), NM_001024879 (Rn) |
RefSeq Protein | NP_036232 (Hs), NP_058574 (Mm), NP_001104301 (Mm), NP_001020050 (Rn) |
UniProtKB | Q9ULA0 (Hs), Q9Z2W0 (Mm), Q4V8H5 (Rn) |
Wikipedia | DNPEP (Hs) |
Enzyme Reaction ![]() |
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Download all structure-activity data for this target as a CSV file
Inhibitors | |||||||||||||||||||||||||||||||||||||||||||||||||||
Key to terms and symbols | View all chemical structures | Click column headers to sort | |||||||||||||||||||||||||||||||||||||||||||||||||
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Inhibitor Comments | |||||||||||||||||||||||||||||||||||||||||||||||||||
As the source of the enzyme used to generate the Ki value for compound 9 is not clear from the referenced article, we have not specified species in the table above. |
M18: Aminopeptidase I: Aminopeptidase A. Last modified on 29/07/2015. Accessed on 01/10/2023. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetomalariapharmacology.org/GRAC/ObjectDisplayForward?objectId=1559.