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Aminopeptidase A

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Target id: 1559

Nomenclature: Aminopeptidase A

Family: M18: Aminopeptidase I

Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 475 2q35 DNPEP aspartyl aminopeptidase
Mouse - 473 1 C4 Dnpep aspartyl aminopeptidase
Rat - 475 9q33 Dnpep aspartyl aminopeptidase
Previous and Unofficial Names Click here for help
ASPEP | DAP | cytosolic aminopeptidase
Database Links Click here for help
Specialist databases
MEROPS M18.002 (Hs)
Other databases
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Enzyme Reaction Click here for help
EC Number:

Download all structure-activity data for this target as a CSV file go icon to follow link

Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
compound 9 [PMID: 1738140] Small molecule or natural product Primary target of this compound Hs Inhibition 6.3 pKi 1
pKi 6.3 (Ki 5.1x10-7 M) [1]
Inhibitor Comments
As the source of the enzyme used to generate the Ki value for compound 9 is not clear from the referenced article, we have not specified species in the table above.


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1. Ocain TD, Rich DH. (1992) alpha-Keto amide inhibitors of aminopeptidases. J Med Chem, 35 (3): 451-6. [PMID:1738140]

How to cite this page

M18: Aminopeptidase I: Aminopeptidase A. Last modified on 29/07/2015. Accessed on 23/05/2024. IUPHAR/BPS Guide to PHARMACOLOGY,