lilotomab   Click here for help

GtoPdb Ligand ID: 9950

Synonyms: Betalutin® | HH1 | tetulomab
Immunopharmacology Ligand
Compound class: Antibody
Comment: Lilotomab is an investigational murine anti-CD37 monoclonal antibody [1]. A radioimmunoconjugate version that can be loaded with the beta radiation-emitting isotope lutetium-177 (known as 177Lu-lilotomab satetraxetan, and as the trade name Betalutin) is being evaluated as a novel radioimmunotherapeutic for the treatment of non-Hodgkin lymphoma [2]. Satetraxetan is the name of the radionuclide chelator, and this is a DOTA derivative known as (p-SCN-Bn)-DOTA (PubChem CID 10123265).
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
10071 lilotomab
Synonyms Click here for help
Betalutin® | HH1 | tetulomab
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 540, 541
Other databases
GtoPdb PubChem SID 374883837
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