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lutikizumab   Click here for help

GtoPdb Ligand ID: 9297

Synonyms: ABT-981 | E26.13-SS-X3 [6]
Immunopharmacology Ligand
Compound class: Antibody
Comment: Lutikizumab (ABT-981) is an investigational monoclonal antibody targeting IL-1α and IL-1β [6], designed using proprietary technology to create dual variable domain antibodies ('DVD-IgTM') [3]. DVD-Igs are single pharmaceutical agents capable of simultaneously targeting two mediators of disease. The unique feature of DVD-Igs is that each arm of the antibody contains two tandem variable domains, each capable of binding a different antigen (see Figure 2 in [6]).
Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record.
Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
10347 lutikizumab
Synonyms Click here for help
ABT-981 | E26.13-SS-X3 [6]
Database Links Click here for help
GtoPdb PubChem SID 318164816
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