GtoPdb Ligand ID: 9188

Comment: Pepcan-12 (a peptide endocannabinoid) is reported as a negative allosteric modulator of the cannabinoid receptor type 1 (CB1 receptor) [1]. Pepcan-12 has identical sequence to the α-hemoglobin-derived dodecapeptide RVD-hemopressin (RVDPVNFKLLSH), proposed as a brain-derived endogenous agonist of CB1 receptors [2].
Compound class Peptide or derivative
Database Links
GtoPdb PubChem SID 315661267