tezepelumab   Click here for help

GtoPdb Ligand ID: 8933

Synonyms: AMG 157 | AMG-157 | MEDI-9929 | MEDI9929 | tezepelumab-ekko | Tezspire®
Approved drug Immunopharmacology Ligand
tezepelumab is an approved drug
Compound class: Antibody
Comment: Tezepelumab is a fully human IgG2λ monoclonal antibody, that is a potential first-in-class agent that blocks the epithelial-cell-derived cytokine thymic stromal lymphopoietin (TSLP- which is an upstream modulator of multiple inflammatory pathways). It is being investigated for its immunomodulatory action.
Classification Click here for help
Compound class Antibody
Approved drug? Yes. FDA (2021)  |  EMA (2022)
International Nonproprietary Names Click here for help
INN number INN
10172 tezepelumab
Synonyms Click here for help
AMG 157 | AMG-157 | MEDI-9929 | MEDI9929 | tezepelumab-ekko | Tezspire®
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 573
Other databases
GtoPdb PubChem SID 310264714
Search PubMed clinical trials tezepelumab
Search PubMed titles tezepelumab
Search PubMed titles/abstracts tezepelumab