minimised relaxin-3 analogue A chain

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Ligands
minimised relaxin-3 analogue A chain

GtoPdb Ligand ID: 8327

Synonyms: minimised relaxin-3 analogue 2 A chain | minimised relaxin-3 analogue 3 A chain

Compound class: Peptide

Comment: A subunit of several human relaxin-3 analogues described in the reference [1]. Forms active heterodimers with a B chain.

Summary
Biological activity
References
Structure
Similar ligands

References
1. Shabanpoor F, Akhter Hossain M, Ryan PJ, Belgi A, Layfield S, Kocan M, Zhang S, Samuel CS, Gundlach AL, Bathgate RA et al.. (2012) Minimization of human relaxin-3 leading to high-affinity analogues with increased selectivity for relaxin-family peptide 3 receptor (RXFP3) over RXFP1. J Med Chem, 55 (4): 1671-81. [PMID:22257012]

References

1. Shabanpoor F, Akhter Hossain M, Ryan PJ, Belgi A, Layfield S, Kocan M, Zhang S, Samuel CS, Gundlach AL, Bathgate RA et al.. (2012)
Minimization of human relaxin-3 leading to high-affinity analogues with increased selectivity for relaxin-family peptide 3 receptor (RXFP3) over RXFP1.
J Med Chem, 55 (4): 1671-81. [PMID:22257012]