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elosulfase alfa   Click here for help

GtoPdb Ligand ID: 7392

Synonyms: BMN 110 | rhGALNS | Vimizim®
Approved drug
elosulfase alfa is an approved drug (EMA & FDA (2014))
Compound class: Peptide
Comment: Elosulfase alfa is a recombinant enzyme replacement therapy for galactosamine (N-acetyl)-6-sulfatase (GALNS, P34059) deficiency. The peptide is translated from the human cDNA expressed in CHO cells [1].
Peptide Sequence Click here for help
MAAVVAATRWWQLLLVLSAAGMGASGAPQPPNILLLLMDDMGWGDLGVYGEPSRETPNLDRMAAEGLLFPNFYSANPLCS
PSRAALLTGRLPIRNGFYTTNAHARNAYTPQEIVGGIPDSEQLLPELLKKAGYVSKIVGKWHLGHRPQFH150PLKHGFD
EWFGSPNCHFGPYDNKARPNIPVYRDWEMVGRYYEEFPINLKT200GEANLTQIYLQEALDFIKRQARHHPFFLYWAVDA
THAPVYASKPFLGTSQRGRYGDAVREIDDSIGKILELLQDLHVADNTFVFFTSDNGAALISAPEQGGSNGPFLCGKQTTF
EGGMREPALAWWPGHVTAGQVSHQLGSIMDLFTTSLALAGLTPPSDRAIDGLNLLPTLLQGRLMDRPIFYYRGDTLMAAT
LGQHKAHFWTWTNSWENFRQGIDFCPGQNVSGVTTHNLEDHTKLPLIFHLGRDPGERFPLSFASAEYQEALSRITSVVQQ
HQEALVPAQPQLNVCNWAVMNWAPPGCEKLGKCLTPPESIPKKCLWSH