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                                                                Synonyms: Myalept® | r-metHuLeptin | R-methuleptin
                                 
                                                         
                            
                            
                            
                                 
                                
                                metreleptin is an approved drug (FDA (2014), EMA (2018)) 
                                                        
                                                    
                                Compound class: 
                                                            Peptide
                                 
                                
                                    
                                        Comment: Metreleptin is a recombinant, 147 amino acid (~16kDa), N-methionyl- analogue of human leptin [1]. Leptin is an adipokine (cytokine secreted by adipose tissue).
                                    
                                 
                            
                            
                          
                                
                                    
                                
                          
                                   
                                   
                                  
                                    
                                    
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Classification ![]()  | 
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| Compound class | Peptide | 
| Approved drug? | Yes. EU EMA (2018) | US FDA (2014) | 
International Nonproprietary Names ![]()  | 
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| INN number | INN | 
| 7808 | metreleptin | 
Synonyms ![]()  | 
                                                        
| Myalept® | r-metHuLeptin | R-methuleptin | 
Database Links ![]()  | 
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| CAS Registry No. | 186018-45-1 | 
| ChEMBL Ligand | CHEMBL2107857 | 
| GtoPdb PubChem SID | 178103905 | 
| Search PubMed clinical trials | metreleptin | 
| Search PubMed titles | metreleptin | 
| Search PubMed titles/abstracts | metreleptin | 
| Wikipedia | Metreleptin |