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α-conotoxin MII [H9A, L15A]   Click here for help

GtoPdb Ligand ID: 4010

Compound class: Peptide
Comment: Derived from Conus magus (Magician's cone snail)
Peptide Sequence Click here for help
GCCSNPVCALEHSNAC
Gly-Cys-Cys-Ser-Asn-Pro-Val-Cys-Ala-Leu-Glu-His-Ser-Asn-Ala-Cys-NH2
Post-translational Modification
Amidation of C-terminal cysteine residue; disulphide bond formation between cysteine residues at postions 2 and 8 and 3 and 16
Chemical Modification
Mutagenesis of the natural sequence substituting histidine reisdue at position 9 for alanine and leucine at residue 15 for alanine