europium-labelled relaxin   Click here for help

GtoPdb Ligand ID: 3874

Synonyms: europium-labelled H2 relaxin
 Ligand is labelled
Compound class: Peptide
Comment: Europium-labelled relaxin is a chemiluminescent probe analogue of human relaxin. It consists of 2 subunits: relaxin (A chain), and relaxin (B chain). For the amino acid sequences of the subunits please see their individual ligand entries.
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
References
1. Hossain MA, Rosengren KJ, Zhang S, Bathgate RA, Tregear GW, van Lierop BJ, Robinson AJ, Wade JD. (2009)
Solid phase synthesis and structural analysis of novel A-chain dicarba analogs of human relaxin-3 (INSL7) that exhibit full biological activity.
Org Biomol Chem, 7 (8): 1547-53. [PMID:19343240]
2. Shabanpoor F, Bathgate RA, Belgi A, Chan LJ, Nair VB, Wade JD, Hossain MA. (2012)
Site-specific conjugation of a lanthanide chelator and its effects on the chemical synthesis and receptor binding affinity of human relaxin-2 hormone.
Biochem Biophys Res Commun, 420 (2): 253-6. [PMID:22425984]