L-363,377   Click here for help

GtoPdb Ligand ID: 2048

Synonyms: L 363377 | L-363377
Compound class: Peptide
Comment: A cyclic peptide. There is some ambiguity surrounding the chirality of L-363,377. The PubChem and ChEMBL entries linked to above each represent a chemical structure for this peptide.
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
References
1. Liapakis G, Tallent M, Reisine T. (1996)
Molecular and functional properties of somatostain receptor subtypes.
Metab Clin Exp, 45 (8 Suppl 1): 12-3. [PMID:8769370]
2. Rohrer SP, Birzin ET, Mosley RT, Berk SC, Hutchins SM, Shen DM, Xiong Y, Hayes EC, Parmar RM, Foor F et al.. (1998)
Rapid identification of subtype-selective agonists of the somatostatin receptor through combinatorial chemistry.
Science, 282 (5389): 737-40. [PMID:9784130]
3. Yang L, Berk SC, Rohrer SP, Mosley RT, Guo L, Underwood DJ, Arison BH, Birzin ET, Hayes EC, Mitra SW et al.. (1998)
Synthesis and biological activities of potent peptidomimetics selective for somatostatin receptor subtype 2.
Proc Natl Acad Sci USA, 95 (18): 10836-41. [PMID:9724791]