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cizutamig   Click here for help

GtoPdb Ligand ID: 14514

Synonyms: CD3med FIT-Ig [2] | EMB-06 | EMB06
Immunopharmacology Ligand
Compound class: Antibody
Comment: Cizutamig (EMB-06) is a humanized B-cell maturation antigen (BCMA; TNFRSF17)-CD3e bispecific antibody that is designed to act as a T cell engager (TCE) [2], to promote depletion of BCMA-expressing B cells and plasma cells for the treatment of autoimmune diseases and B cell malignancies.
Selectivity at catalytic receptors
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
B cell maturation antigen Hs Antibody Binding - - - 2
⤷ [2]
Selectivity at other protein targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
CD3e Hs Antibody Binding - - - 2
⤷ [2]