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narsoplimab   Click here for help

GtoPdb Ligand ID: 14317

Synonyms: narsoplimab-wuug | OMS-721 | OMS721 | Yartemlea®
Approved drug
narsoplimab is an approved drug
Compound class: Antibody
Comment: Narsoplimab (OMS721) is a fully human IgG4 monoclonal antibody against mannan-binding lectin-associated serine protease 2 (MASP-2) [2].
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
Selectivity at enzymes
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
MBL associated serine protease 2 Primary target of this compound Hs Inhibitor Binding 10.1 pKd - 2
⤷ pKd 10.1 (Kd 8.9x10-11 M) [2]
Description: Binding affinity for active form of human MASP2