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bocunebart   Click here for help

GtoPdb Ligand ID: 14313

Synonyms: ALD-1910 | ALD1910 | LU AG-09222 | Lu AG09222 | Lu-AG09222 | LuAG09222
Compound class: Antibody
Comment: Bocunebart (Lu AG09222 from Lundbeck; formerly ALD1910) is a humanized monoclonal antibody that targets both isoforms of PACAP (PACAP-27 and PACAP-38) [1-2]. It is designed to disrupt PACAP signaling via its receptors as a mechanism to reduce migraine episodes [2-3]. The PACAP epitope engaged by Lu AG09222 is nonlinear, with interactions at amino acids in positions 19, 22, 23, and/or 27 required for potent binding.
Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
13356 bocunebart
Synonyms Click here for help
ALD-1910 | ALD1910 | LU AG-09222 | Lu AG09222 | Lu-AG09222 | LuAG09222
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 1747
Other databases
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