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fesomersen   Click here for help

GtoPdb Ligand ID: 14081

Synonyms: IONIS-FXI-LRx
Compound class: Nucleic acid
Comment: Fesomersen (IONIS-FXI-LRx) is a conjugated antisense oligonucleotide that selectively inhibits the expression of factor XI [1]. It is being explored as an anticoagulation therapy.
We provide the basic nucleotide sequence, without the modifications outlined in the INN record for this drug.
No information available.
Summary of Clinical Use Click here for help
Fesomersen is being investigated as an anticoagulation therapy.
Clinical Trials
Clinical Trial ID Title Type Source Comment References
NCT03582462 A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Doses of IONIS FXI-LRx in up to 84 Healthy Volunteers Phase 1 Interventional Ionis Pharmaceuticals, Inc.