GtoPdb is requesting financial support from commercial users. Please see our sustainability page for more information.

fesomersen   Click here for help

GtoPdb Ligand ID: 14081

Synonyms: IONIS-FXI-LRx
Compound class: Nucleic acid
Comment: Fesomersen (IONIS-FXI-LRx) is a conjugated antisense oligonucleotide that selectively inhibits the expression of factor XI [1]. It is being explored as an anticoagulation therapy.
We provide the basic nucleotide sequence, without the modifications outlined in the INN record for this drug.
Selectivity at enzymes
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
coagulation factor XI Hs None - - - - 1
⤷ Synthesis reducer [1]