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                                                                Synonyms: IONIS-FXI-LRx
                                 
                                                         
                            Compound class: 
                                                            Nucleic acid
                                 
                                
                                    
                                        Comment: Fesomersen (IONIS-FXI-LRx) is a conjugated antisense oligonucleotide that selectively inhibits the expression of factor XI [1]. It is being explored as an anticoagulation therapy. 
                            
                            
                          
                                
                                    
                                
                          
                                   
                                   
                                  
                                    
                                    
                                    We provide the basic nucleotide sequence, without the modifications outlined in the INN record for this drug.  | 
                                    
Classification ![]()  | 
                                                    |
| Compound class | Nucleic acid | 
| Compound subclass | Antisense oligonucleotide (ASO) | 
| Target | Factor XI | 
International Nonproprietary Names ![]()  | 
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| INN number | INN | 
| 11638 | fesomersen | 
Synonyms ![]()  | 
                                                        
| IONIS-FXI-LRx | 
Database Links ![]()  | 
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| CAS Registry No. | 2380135-03-3 (source: WHO INN record) | 
| GtoPdb PubChem SID | 518520708 | 
| Search PubMed clinical trials | fesomersen | 
| Search PubMed titles | fesomersen | 
| Search PubMed titles/abstracts | fesomersen |