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SFKN-NH2   Click here for help

GtoPdb Ligand ID: 13997

Compound class: Peptide
Comment: SFKN-NH2 is a four amino acid analogue of human neuropeptide S (NPS) [1]. The peptide exhibits bias towards the calcium mobilisation pathway over the cAMP pathway.
References
1. Clark SD, Kenakin TP, Gertz S, Hassler C, Gay EA, Langston TL, Reinscheid RK, Runyon SP. (2017)
Identification of the first biased NPS receptor agonist that retains anxiolytic and memory promoting effects with reduced levels of locomotor stimulation.
Neuropharmacology, 118: 69-78. [PMID:28267583]