batoclimab

Home
Ligands
batoclimab

GtoPdb Ligand ID: 13805

Synonyms: HBM9161 | HL161 | HL161ANS | IMVT-1401 | RVT-1401

Comment: Batoclimab (HBM9161; IMVT-1401) is a fully human anti-FcRn (FCGRT) monoclonal antibody [1]. It was developed by Harbour BioMed for the treatment of IgG-mediated autoimmune diseases.

Summary
Biological activity
Clinical data
References
Immunopharmacology

References
1. Yap DYH, Hai J, Lee PCH, Zhou X, Lee M, Zhang Y, Wang M, Chen X. (2021) Safety, tolerability, pharmacokinetics, and pharmacodynamics of HBM9161, a novel FcRn inhibitor, in a phase I study for healthy Chinese volunteers. Clin Transl Sci, 14 (5): 1769-1779. [PMID:33742786]

References

1. Yap DYH, Hai J, Lee PCH, Zhou X, Lee M, Zhang Y, Wang M, Chen X. (2021)
Safety, tolerability, pharmacokinetics, and pharmacodynamics of HBM9161, a novel FcRn inhibitor, in a phase I study for healthy Chinese volunteers.
Clin Transl Sci, 14 (5): 1769-1779. [PMID:33742786]