enlonstobart   Click here for help

GtoPdb Ligand ID: 13789

Synonyms: SG-001 | SG001
Approved drug
enlonstobart is an approved drug
Compound class: Antibody
Comment: Enlonstobart (SG001) is a fully humanised anti-PD-1 (PDCD1) monoclonal antibody. It was developed to treat advanced solid tumours by blocking the inhibitory the PD-1/PD-L1/L2 immune checkpoint.
Bioactivity Comments
We have been unable to uncover quantitative data that supports antibody binding to its proposed target.
Selectivity at other protein targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
programmed cell death 1 (CD279) Primary target of this compound Hs Antibody Binding - - -